Stroke Volume and Cardiac Output (2024)

STROKE VOLUME AND CARDIAC OUTPUT

Stroke Volume and Cardiac Output (1)

Illustration from Anatomy & Physiology, Connexions Web site. http://cnx.org/content/col11496/1.6/, Jun 19, 2013.

Stroke Volume

Stroke Volume (SV)is the volume of blood in millilitres ejected from theeach ventricledue to the contraction of the heart muscle which compresses theseventricles.

SV is the difference between end diastolic volume (EDV) and end systolic volume (ESV). Multiple factors can affect SV, eg. factors that change either EDV or ESV will change SV. The three primary factors that regulate SV are preload, afterload and contractility.

Heart rate (HR) also affects SV. Changes in HR aloneinversely affects SV. However, SVcan increase when there is an increase in HR (duringexercise for example)whenothermechanisms are activated, but when these mechanisms fail, SV cannot be maintained during anelevated HR. These mechanisms include increased venous return, venous constriction, increased atrial and ventricular inotropy and enhanced rate of ventricular relaxation.

TheODM+calculates SV by multiplying theStroke Distance (SD)by a constant accessed from the built-in patientnomogram.

Normal values for a resting healthy individual would be approximately 60-100mL. Patients undergoing surgery or in critical illness situations may require higher than normal SV and it may be more appropriate to aim for optimal rather than normal SV. See Stroke Volume Optimisation and Improved Outcomes.

Stoke Volume Index

Stroke Volume Index (SVI) relates SV to body surface area (BSA), thus relating heart performance to the size of the individual. The unit of measurement is millilitres per square metre (ml/m2).

SVI = SV/BSA

Normal values for a resting healthy individual would be approximately 35-65mL/m2. Patients undergoing surgery or in critical illness situations may require higher than normal SVI and it may be more appropriate to aim for optimal rather than normal SVI.

Cardiac Output

Cardiac Output (CO)is the amount of blood the heart pumps from each ventricle perminute. It is usually expressed in litres per minute (L/min).

CO = HR x SV

Changes in either HR or SV can alter CO. Impaired regulationof SV (including preload, afterload and contractility) can have a significant adverse affect on CO.

​Normal values for a resting healthy individual would be approximately 5-8L. Patients undergoing surgery or in critical illness situations may require higher than normal CO and it may be more appropriate to aim for optimal rather than normal CO.

Cardiac Index

Cardiac index (CI) is the cardiac output proportional to the body surface area (BSA).The unit of measurement is litres per minute per square metre (L/min/m2).

CI= CO x BSA

​Normal values for a resting healthy individual would be approximately 2.5-4.2L/m2. Patients undergoing surgery or in critical illness situations may require higher than normal CI and it may be more appropriate to aim for optimal rather than normal CI.

Suggested Reading

​Dvorak G.O., Hemodynamic Monitoring: Invasive and Non Invasive Clinical Application. 2008 ed 4. Saunders.

Grossman S., and Porth C.M., Porth’s Pathophysiology: Concepts ofAltered Health States. 2013 ed 9. Lippincott Williams & Wilkins.

Klabunde R.E., Cardiovascular Physiology Concepts. 2005. Lippincott Williams & Wilkins.

Porter R.S., The Merck Manual of Diagnosis and Therapy. 2011 ed 19. Wiley. See alsowww.merckmanuals.com

Stroke Volume and Cardiac Output (2024)

FAQs

Stroke Volume and Cardiac Output? ›

Cardiac output is the product of heart rate (HR) and stroke volume (SV) and is measured in liters per minute. HR is most commonly defined as the number of times the heart beats in one minute. SV is the volume of blood ejected during ventricular contraction or for each stroke of the heart.

What is the relationship between cardiac output and stroke volume? ›

Stroke volume is the amount of blood ejected from the ventricle with each cardiac cycle. It can be readily calculated by subtracting the end-systolic volume from the end-diastolic volume. Multiplying the stroke volume by the heart rate yields the cardiac output, typically reported in liters per minute.

What is meant by stroke volume? ›

The definition of stroke volume is the volume of blood pumped out of the left ventricle of the heart during each systolic cardiac contraction.

How do you calculate cardiac output? ›

As we all know, Cardiac output is the total volume of blood that heart pumps every minute. The formula used to calculate cardiac output is given as CO = HR × SV. SV- Stroke volume — the amount of blood circulated by the heart with each beat.

What is stroke volume and cardiac output of human? ›

Cardiac output is the volume of blood pumped out of the heart by the ventricles per minute. Hence, stroke volume is equal to 60 to 70 ml of blood/heartbeat and cardiac output is equal to 3 to 5 liters of blood per minute.

What is the relationship between cardiac output and stroke volume quizlet? ›

Cardiac output is the product of the stroke volume and heart rate. An injury or illness such as a heart attack can affect the contractility and therefore the cardiac output and stroke volume.

Does cardiac output decrease when stroke volume decreases? ›

The cardiac output is the volume of blood pumped by the heart each minute. It can be calculated as stroke volume times heart rate. Factors that alter stroke volume or heart rate will change cardiac output. Normally it is about 5 L/min (70 mL/beat × 72 beats/min).

What is the definition of cardiac output? ›

Cardiac output (CO) is the amount of blood pumped by the heart minute and is the mechanism whereby blood flows around the body, especially providing blood flow to the brain and other vital organs.

What is a good stroke volume? ›

Normal values for a resting healthy individual would be approximately 60-100mL. Patients undergoing surgery or in critical illness situations may require higher than normal SV and it may be more appropriate to aim for optimal rather than normal SV. See Stroke Volume Optimisation and Improved Outcomes.

What's a normal cardiac output? ›

Cardiac output is calculated by multiplying the stroke volume by the heart rate. Stroke volume is determined by preload, contractility, and afterload. The normal range for cardiac output is about 4 to 8 L/min, but it can vary depending on the body's metabolic needs.

What is considered high cardiac output? ›

In terms of cardiac output, a high cardiac output state is defined as a resting cardiac output greater than 8 L/min or a cardiac index of greater than 4.0/min/m2 , and heart failure occurs when that cardiac output is insufficient to supply the demand.

Is high cardiac output good? ›

Higher cardiac output can be a good thing when exercise creates the need for more blood flow. But this is different because it's not a healthy cause. Your body may need more blood because it's using more oxygen than normal or your blood is going around your smallest arteries (arterioles) instead of into them.

Why does cardiac output increase with exercise? ›

Cardiac output during exercise increases greatly owing to the relatively high heart rates that are achieved during exercise. Heart rate increases proportionately with workload until heart rates close to maximal are attained.

What determines stroke volume? ›

However, stroke volume depends on several factors such as heart size, contractility, duration of contraction, preload (end-diastolic volume), and afterload. Corresponding to the oxygen uptake, women's need for blood flow does not decrease and a higher cardiac frequency makes up for their smaller stroke volume.

What decreases stroke volume? ›

Dehydration reduces stroke volume and cardiac output during exercise because of impaired cardiac filling and venous return, not left ventricular function.

How is stroke volume calculated? ›

The SV volume may be calculated as the difference between the left ventricular end-diastolic volume and the left ventricular end-systolic volume (ESV).

What is the relation between stroke and heart? ›

Stroke induced cardiac damage may lead to fatality or potentially lifelong cardiac problems (such as heart failure), or to mild and recoverable damage such as neurogenic stress cardiomyopathy (NSC) and Takotsubo cardiomyopathy.

What is the difference between stroke volume and cardiac output quizlet? ›

stroke volume(SV) is the volume of blood ejected by a ventricle in a single contraction. Cardiac output (CO) is the amount of blood pumped by the left ventricle in 1 minute: CO(in mL/min) = HR (in beats/mn) x SV ( in mL/ beat).

Are heart rate and stroke volume inversely related? ›

The SV changes related inversely to the HR changes, thus diminishing the effect of HR on LVO. Thus, under otherwise stable conditions, it appears that the beat-to-beat fluctuations in HR are counterbalanced by changes in SV.

Is cardiac output calculated by multiplying the stroke volume? ›

Cardiac Output Formula

Cardiac output (CO) is the volume of blood the heart pumps per minute. Cardiac output is calculated by multiplying the stroke volume by the heart rate. Stroke volume is determined by preload, contractility, and afterload.

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