About clobetasol (2024)

Clobetasol is a steroid medicine that's used on the skin to treat swelling, itching and irritation. Although it is a steroid, it's not the same as anabolic steroids.

Clobetasol is a very strong steroid. It works by reducing the swelling (inflammation), itching and pain caused by an allergic reaction or irritation.

It can help with skin problems such as:

Clobetasol is available on prescription only.

It comes as a cream, ointment, scalp treatment and shampoo.

There is also a cream and ointment called clobetasone which sounds similar to clobetasol. Clobetasone is much milder and you can buy it from pharmacies or shops.

Clobetasol is also available as a medicine combined with an antibiotic (neomycin sulfate) and an antifungal (nystatin). This is only available on prescription.

Key facts

  • Do not put clobetasol on your face unless your doctor says it's OK. It can make some skin problems on the face worse.
  • Clobetasol starts to work after a few days. You can use it for up to 4 weeks.
  • If you have applied clobetasol to your skin, wait at least 30 minutes before using another product, like a moisturiser.
  • If your doctor has prescribed high doses of clobetasol to control your symptoms you may need to carry a steroid emergency card. Ask your pharmacist or doctor.
  • Dried skin cream on your clothes or bedding makes them more likely to catch fire (flammable). Avoid naked flames.
  • If you use clobetasol for a long time your doctor might advise you to reduce your dose gradually to avoid withdrawal reactions.

Page last reviewed: 21 October 2022
Next review due: 21 October 2025

About clobetasol (2024)

FAQs

What is the problem with clobetasol? ›

You're more likely to have a serious side effect if you use clobetasol on a large area of skin for a long time. Clobetasol cream contains cetostearyl alcohol, which may cause a skin reaction in the area you are treating, and chlorocresol, which may cause an allergic reaction.

How long can you safely use clobetasol? ›

Don't use clobetasol for more than 2 weeks at a time (4 weeks for the shampoo) unless directed by your provider. In addition, if you suddenly stop using clobetasol after having done so for a long time and over a large skin area, you might experience topical steroid withdrawal (TSW).

Why is clobetasol being recalled? ›

Taro Pharmaceuticals U.S.A. Issues Voluntary Nationwide Recall of Clobetasol Propionate Ointment USP, 0.05%, 60 g Tubes, Lot AC13786 Due to Microbial Contamination.

What does clobetasol heal? ›

Clobetasol topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various scalp and skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body) and eczema (a skin disease that causes the skin to be dry and itchy and ...

What happens if clobetasol gets in your bloodstream? ›

Using clobetasol continuously for a long time can mean some of the medicine gets into your bloodstream. If this happens, there's a very small chance it can cause serious side effects, such as adrenal gland problems, high blood sugar (hyperglycaemia) or problems with your eyesight.

Is clobetasol bad for your liver? ›

For people with liver problems: This drug is processed by your liver. If you have severe liver problems, your body may not be able to break down this drug as well. This could cause the drug to build up in your body. This may increase your risk of side effects.

Is clobetasol a strong steroid? ›

Clobetasol is a steroid medicine that's used on the skin to treat swelling, itching and irritation. Although it is a steroid, it's not the same as anabolic steroids. Clobetasol is a very strong steroid. It works by reducing the swelling (inflammation), itching and pain caused by an allergic reaction or irritation.

What is the success rate of clobetasol? ›

Clobetasol is effective at stimulating hair growth. Research has shown hair regrowth was stimulated in about 20 to 25% of people who used clobetasol ointment and in about 47% of people who used clobetasol foam.

What over the counter medicine is comparable to clobetasol propionate? ›

Examples of other drugs that may be used to treat skin disorders that cause itching or inflammation include:
  • corticosteroids other than Clobex, such as: mometasone lotion (Elocon) hydrocortisone 2.5% lotion. ...
  • over-the-counter (OTC) lotions, such as: Aveeno lotion. CeraVe lotion.
May 31, 2020

Who should not use clobetasol? ›

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, other skin conditions (such as rosacea, perioral dermatitis), immune system problems. Do not use if there is an infection or sore in the area to be treated.

Can you just stop using clobetasol? ›

Stopping clobetasol

Talk to your doctor before stopping treatment if you've been using clobetasol for a long time. They may tell you to gradually use less of it, and use it less often, before you stop completely. This reduces the chance of your symptoms coming back.

Does clobetasol suppress your immune system? ›

Clobetasol propionate exerts antiinflammatory, immunosuppressive and antimitotic effects influencing the growth, differentiation and function of various cells and inhibiting cytokine production. Seven different dosage forms are available to deliver the drug to the living cells of the skin.

How do you know if clobetasol is working? ›

Official answer. It takes about one to three days for clobetasol propionate to start working when it is being used to treat eczema. Some improvement in symptoms such as inflammation (redness) and itching, should be noticed within this time.

How many days in a row can you use clobetasol? ›

by Drugs.com

Treatment should not exceed two weeks for eczema/dermatitis or psoriasis and no more than 50 grams of cream or ointment should be used per week.

Do you wash off clobetasol? ›

If you are using clobetasol propionate shampoo, use it as you normally would use a shampoo but leave it on your scalp for 15 minutes before rinsing out. Avoid contact with the lips and eyes.

Does clobetasol propionate weaken the immune system? ›

Clobetasol propionate exerts antiinflammatory, immunosuppressive and antimitotic effects influencing the growth, differentiation and function of various cells and inhibiting cytokine production. Seven different dosage forms are available to deliver the drug to the living cells of the skin.

Is clobetasol the strongest steroid? ›

Clobetasol cream is much stronger than other steroid creams such as hydrocortisone 1% strength. Most people only need to use clobetasol 1 or 2 times a day for 1 week. A doctor may suggest that you use it for longer than 1 week.

Does topical clobetasol have systemic effects? ›

Adverse Effects

Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects. These include reversible hypothalamic–pituitary–adrenal (HPA) axis suppression, manifestations of Cushing's disease, hyperglycemia, and glucosuria.

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